large rash, itchy and still spreading and slightly swollen; This is a spontaneous report received from a Consumer or other non HCP. A 60-year-old female patient received pneumococcal 20-val conj vac (dipht CRM197 protein) (PREVNAR 20), on 21Jan2025 at 15:48 as dose number unknown, 0.5ml single (Lot number: LJ5283, Expiration Date: 31May2026) at the age of 60 years intramuscular, in left deltoid for immunisation; influenza vaccine inact split 3v (FLULAVAL), on 21Jan2025 as dose number unknown, single (Lot number: 9H5J5, Expiration Date: 30Jun2025) for immunisation. The patient’s relevant medical history was not reported. The patient took concomitant medications. The following information was reported: RASH PRURITIC (non-serious) with onset 26Jan2025, outcome “not recovered”, described as “large rash, itchy and still spreading and slightly swollen”. Therapeutic measures were taken as a result of rash pruritic. Additional information: Reporter (Medical assistant) was calling from a doctor’s office, because they have a patient who had an adverse reaction to the Prevnar 20. The doctor was asking if there was anything else, she was using hydrocortisone cream (Treatment) and the doctor was recommending Benadryl for the adverse reaction (Treatment). Reporter stated that the patient was having a large rash, itchy and still spreading and slightly swollen. The patient was on several medications, Not on reporting day. Reporter stated, she still experiencing the reaction.