Right upper quadrant pain; This non-serious case was reported by a physician via call center representative and described the occurrence of upper abdominal pain in a adult male patient who received HAB (Twinrix) for prophylaxis. On 14-AUG-2024, the patient received the 2nd dose of Twinrix. On an unknown date, an unknown time after receiving Twinrix, the patient experienced upper abdominal pain (Verbatim: Right upper quadrant pain). Rechallenge with Twinrix was positive. The outcome of the upper abdominal pain was not resolved. It was unknown if the reporter considered the upper abdominal pain to be related to Twinrix and Twinrix Pre-Filled Syringe Device. It was unknown if the company considered the upper abdominal pain to be related to Twinrix and Twinrix Pre-Filled Syringe Device. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Linked case(s) involving the same patient: US2024123891 Additional Information: GSK Receipt Date: 31-DEC-2024 The patient experienced right upper quadrant pain after Twinrix second dose. This pain persisted. Follow up by Safety Team was accepted to his personal email.; Sender’s Comments: US-GSK-US2024123891:same reporter