Patient had the vaccine on May 23, 2024. That evening he developed a headache, took Tylenol with no relief. Headache worsened that night and over the next two days. Took Tylenol around the clock. On day 3 his neck became very stiff and painful, unable to rotate it at all. PCP notified. Next day both his shoulders when he woke up were stiff and unable to move them. Severe pain if he tried. Was unable to get out of bed. He was like a stiff man. Next day his hips and knees hurt also. He was a mess. Unable to get up out of bed to use toilet without maximum help. Dr. a rheumatologist was contacted and an appt made for the following week. After a complete interview and examination he told us patient had Polymyalgia Rheumatica, that was trigged by his body immune system reacting to the Prevnar vaccine. Was begun on Prednisone 40 mg and within 2 days he felt much better. He was slowly tapered down to the present 5 mg and has been unable x 2 tries to reduce further or the initial symptoms return. The fatigue was unbelievable! He would lay down and within 2 minutes he would be sound asleep. The Prednisone had no effect on this fatigue.