the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy; the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy; the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy; the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy; the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy; swelling at the injection site; This is a spontaneous report received from a Nurse from medical information team. A 27-year-old female patient (pregnant) received rsv vaccine prot.subunit pref 2v (ABRYSVO), on 16Jan2025 as dose 1, single (Batch/Lot number: unknown), in right arm for maternal immunisation. The patient’s relevant medical history and concomitant medications were not reported. The following information was reported: VACCINATION SITE SWELLING (non-serious) with onset 18Jan2025, outcome “not recovered”, described as “swelling at the injection site”; VACCINATION SITE WARMTH (non-serious), VACCINATION SITE ERYTHEMA (non-serious), VACCINATION SITE INFLAMMATION (non-serious), VACCINATION SITE PAIN (non-serious), VACCINATION SITE PRURITUS (non-serious) all with onset 18Jan2025, outcome “not recovered” and all described as “the area where the vaccine was given was warm, red, and inflamed and it was also painful and itchy”. Therapeutic measures were taken as a result of vaccination site warmth, vaccination site erythema, vaccination site inflammation, vaccination site pain, vaccination site pruritus, vaccination site swelling. Additional information: Patient was treated with Benadryl but didn’t help. Patient was asking for advise. Patient was advised by the reporter to use cold compresses, continuous Benadryl as needed or she could switch to Zyrtec.