headaches; brain fog; This spontaneous case was reported by a patient and describes the occurrence of HEADACHE (headaches) and BRAIN FOG (brain fog) in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. No Medical History information was reported. In 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular use) 1 dosage form. In 2021, received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular use) dosage was changed to 1 dosage form. In 2021, the patient experienced HEADACHE (headaches) (seriousness criterion medically significant) and BRAIN FOG (brain fog) (seriousness criterion medically significant). At the time of the report, HEADACHE (headaches) and BRAIN FOG (brain fog) had not resolved. No concomitant medications were reported. It was reported that patient had received the covid vaccine when it came out, the first dose was fine then a month later, received the 2nd shot. It was from a different batch. Patient developed headaches, a terrible brain fog. Patient stated that mid-April will be the 4th year that have suffered with this. Patient would like to know if Moderna would be able to help, or if something to reverse the shot. It also stated that patient was permanently disabled from the Moderna shot and would like to get this head out that Moderna and that vaccine did a job to the patient. It was unknown if the patient experienced any additional symptoms/events. No treatment medications were reported.; Reporter’s Comments: Company comment: The benefit-risk relationship of product is not affected by this report.